Tot sobre l'acetat de Megestrol en pols

 

  Revisions 1.Megestrol acetat (CAS: 595-33-5)
  2. Com funciona l'acetat de Megestrol?
  3. Com es pren la pols d'acetat de megestrol millor?
  4. Quines precaucions especials Abans de prendre l'acetat de megestrol en pols?
  5. Com puc prendre l'acetat de megestrol en pols?
  6.Utilitzeu el pols de acetat de Megestrol en poblacions específiques
  7. Què he de saber sobre l'emmagatzematge i eliminació d'aquest medicament?
  Efectes secundaris de 8.Megestrol acetat
  S'hauria de considerar acuradament l'ús de l'acetat de 9.Megestrol per a l'augment de pes
  10. Quina és la informació més important que hauria de saber sobre Megestrol Acetate powder?
  11. On puc obtenir més informació sobre l'acetat de Megestrol?

 


 

Vídeo de pols d'acetat de Megestrol

 

 


I. Pols d'acetat de mestrol Personatges bàsics:

 

Nom: Pols d'acetat Megestrol
CAS: 595-33-5
Fórmula molecular: C19H26O3
Pes molecular: 302.41
Punt de fusió: 244-246 ° C
Temps d'emmagatzematge: Temperatura ambient
Color: Pols blanc

 


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1. Acetat de Megestrolressenyes (CAS:595-33-5)aasraw

 

L'acetat de Megestrol és un tipus de tractament hormonal. També es diu Megace o megestrol (595-33-5). És una versió artificial de l'hormona progesterona. La progesterona és una de les hormones femenines, però els homes també produeixen una petita quantitat d'aquesta.
La pols d'acetat de Megestrol és un tractament per als següents càncers que han tornat o es van estendre des d'on van començar.

♦ càncer de mama
♦ càncer de ventre
També és un tractament per la mala apetència. El seu metge podria suggerir que la prengui si ha perdut pes a causa del càncer o el seu tractament. Els metges també poden utilitzar-lo com a tractament per a dones que tenen fluxos calents a causa del seu càncer o el seu tractament.

 


 

2. Com Acetat de Megestroltreballar?aasraw

 

L'acetat de Megestrol és un tipus de teràpia hormonal. Les hormones són substàncies químiques produïdes per glàndules del cos, que entren al torrent sanguini i causen efectes en altres teixits. (Per exemple, l'hormona testosterona realitzada en els testicles és responsable de les característiques masculines com l'aprofundiment de la veu i l'augment del cabell del cos). L'ús de la teràpia hormonal per tractar el càncer es basa en l'observació que els receptors per a les hormones específiques que es necessiten per al creixement cel·lular es troben a la superfície d'algunes cèl·lules tumorals. Les teràpies hormonals funcionen per; aturar la producció d'una determinada hormona, bloquejar els receptors d'hormones o substituir agents químicament similars per a l'hormona activa, que no poden ser utilitzats per la cèl·lula tumoral. Els diferents tipus de teràpies hormonals es classifiquen per la seva funció i / o el tipus d'hormona que s'efectua.
L'acetat de Megestrol és a progestina (una forma artificial de l'hormona progesterona). Té propietats que interfereixen amb el cicle normal d'estrogen. Això interfereix amb l'estimulació del creixement cel·lular en cèl·lules tumorals dependents d'estrògens. També es pensa que hi ha algun efecte directe sobre el revestiment de la paret uterina (endometri).
Un efecte secundari de l'acetat de Megestrol ha estat l'augment de pes. El mecanisme exacte d'aquest efecte no està clar, però els efectes generen un augment del greix corporal. Aprofitant aquest efecte secundari, l'acetat de Megestrol ha estat estudiat i utilitzat per tractar pèrdua severa de l'apetit (anorèxia), malbaratament muscular (caquexia) i pèrdua de pes relacionada amb el càncer i la sida.

El treball d'acetat de Megestrol, l'acetat de Megestrol en pols (595-33-5) és un tipus de tractament hormonal i és una versió artificial de l'hormona progesterona.

 


 

3. Com es pren millor mètode d'acetat de megestrol?aasraw

 

Utilitzeu aquest medicament (pols de acetat de Megestrol) tal com ha ordenat el metge. Llegiu tota la informació que se us ha proporcionat. Seguiu totes les instruccions de prop.
♦ Per obtenir el màxim benefici, no us perdeu dosis.
♦ Manténgase prenent aquest medicament (pols de acetat de Megestrol) tal com li han dit el seu metge o altre proveïdor d'atenció mèdica, fins i tot si se sent bé.

Què faig si em trobo a faltar una dosi?

♦ Prengui una dosi perduda a mesura que ho pensi.
♦ Si està a prop del temps de la seva pròxima dosi, ometeu la dosi perduda i torneu al vostre temps normal.
♦ No prengui dosis 2 al mateix temps o dosis addicionals.

 


 

4. Quines precaucions especials Abans de prendre l'acetat de megestrol en pols?aasraw

 

♦ Digueu-li al seu metge i farmacèutic si és al·lèrgic a l'acetat de megestrol en pols, a qualsevol altre medicament o a qualsevol dels ingredients inactius del pols de maceració de megestrol, suspensió o suspensió concentrada. Pregunti al seu metge o farmacèutic per obtenir una llista dels ingredients inactius.
♦ tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention antibiotics and indinavir (Crixivan). Your doctor may need to adjust the doses of your medications or monitor you carefully for side effects.
♦ tell your doctor if you have or have ever had a blood clot anywhere in the body, a stroke, diabetes, or kidney or liver disease.
♦ tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking megestrol acetate powder, call your doctor immediately. megestrol acetate powder may harm the fetus. Do not breast-feed while you are taking megestrol acetate powder.
♦ you should know that megestrol acetate powder may interfere with the normal menstrual cycle (period) in women. However, you should not assume that you cannot become pregnant. Use a reliable method of birth control to prevent pregnancy.
♦ if you are having surgery, including dental surgery, during or shortly after your treatment, tell the doctor or dentist that you are taking megestrol acetate powder.


 

5. Com puc prendre l'acetat de megestrol en pols?aasraw

Realitzeu exactament el que prescriu el vostre metge. No prengui quantitats més grans o petites o per més temps del recomanat. Seguiu les indicacions de l'etiqueta de la vostra prescripció.
Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Megace ES contains a higher concentration of megestrol acetate powder than Megace. If your doctor changes your brand, strength, or type of megestrol acetate powder, your dosage needs may change. Ask your pharmacist if you have any questions about the medicine you receive at the pharmacy.
Your dosage needs may change if you have surgery, are ill, are under stress, or have an infection. Do not change your medication dose or schedule without your doctor’s advice. Store at room temperature away from moisture and heat.

 


 

6. Utilitzar Acetat de Megestrol Powder in specific populationsaasraw

 

 Embaràs

Pregnancy Category X [see Warnings and Precautions (5.2)]. No adequate animal teratology information is available at clinically relevant doses. Pregnant rats treated with low doses of Megestrol acetate powder (0.02-fold the recommended clinical dose) resulted in a reduction in fetal weight and number of live births, and feminization of male fetuses.

 Mares d'infermeria

Because of the potential for adverse effects on the newborn, nursing should be discontinued if Megestrol acetate powder is required.

 Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

 Geriatric Use

Clinical studies of Megestrol acetate powder in the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with AIDS did not include sufficient numbers of patients aged 65 years and older to determine whether they respond differently than younger patients. Other reported clinical experience has not identified differences in responses between elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
Megestrol acetate powder  is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

 Use in Women

Megestrol acetate powder has had limited use in HIV infected women. All 10 women in the clinical trials reported breakthrough bleeding. Megestrol acetate powder is a progesterone derivative, which may induce vaginal bleeding in women.

The most comprehensive introduction for Megestrol acetate powder | AASraw

 


 

7. Què he de saber sobre l'emmagatzematge i eliminació d'aquest medicament?aasraw

 

Mantingui aquest medicament al contenidor que hagi entrat, ben tancat i fora de l'abast dels nens. Deseu-la a temperatura ambient i lluny de l'excés de calor i humitat (no al bany).
És important mantenir tots els medicaments fora de la vista i l'abast dels nens, ja que els contenidors (com els que pateixen medicaments setmanals i els que usen gotes d'ulls, cremes, pegats i inhaladors) no són resistents als nens i els nens petits poden obrir-los fàcilment. Per protegir els infants de l'enverinament, sempre bloquegeu els casquets de seguretat i col·loqueu immediatament el medicament en un lloc segur: un que està fora i fora de la vista i l'abast.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. find www.aasraw.com for more information if you do not have access to a take-back program.

 


 

8. Megestrol acetateefectes secundarisaasraw

 

Megace (megestrol acetate, USP) Oral Suspension is a man-made chemical similar to the female hormone progesterone used to treat loss of appetite and weight loss because of disease, and is also used in the treatment of advanced breast cancer and endometrial cancer. Megace is available in generic form. Common side effects of Megace include:
· weight gain
· Canvis d'apetit
· stomach upset
· Diarrea
· gas
· Erupció cutània
· trouble sleeping (insomnia)
· weakness
· decreased sexual ability/desire
· impotence
· trouble having an orgasm
Febre
Women may experience changes in menstrual periods, including unpredictable vaginal bleeding.The recommended adult initial dosage of Megace Oral Suspension is 800 mg/day (20 mL/day). Megace may interact with insulin or oral diabetes medicine and may decrease the effects of these medications, and blood sugar levels may increase. If you have diabetes, monitor blood sugar and talk to your doctor if you notice unusual changes. Megace may interact with indinavir, or insulin or oral diabetes medications. Tell your doctor all medications and supplements you use. Megace must not be used during pregnancy. It may cause harm to a fetus. Women of childbearing age should use birth control while using this medication. This medication may pass into breast milk and could have undesirable effects on a nursing infant. Breast-feeding is not recommended while using this drug.
Our Megace (megestrol acetate, USP) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Aquesta no és una llista completa dels efectes secundaris i altres poden passar. Truqui al seu metge per obtenir consells mèdics sobre els efectes secundaris. Podeu informar els efectes secundaris a la FDA a 1-800-FDA-1088.

 


 

9. Megestrol Acetate Use for Weight Gain Should Be Carefully Consideredaasraw

 

The most comprehensive introduction for Megestrol acetate powder | AASraw

The most comprehensive introduction for Megestrol acetate powder | AASraw

Megestrol acetate (595-33-5) is a progestational agent with a powerful effect on appetite. It was initially used as a contraceptive agent; however, the common side effect of weight gain led to its current use as an orexigenic agent. Administration of MA results in substantial increases in appetite and body weight in patients with HIV-associated wasting and in those with cancer. MA is currently Food and Drug Administration (FDA) approved for HIV-associated weight loss. In addition, both in healthy, community-dwelling older individuals and elderly people residing in long-term care facilities, the use of MA results in a robust increase in body weight. The use of orexigenic agents such as MA in these settings is appropriate because involuntary weight loss has been associated with increased mortality. Indeed, MA has a greater effect on body weight and appetite than other orexigenic agents such as dronabinol and eicospentaenoic acid. However, in older people and patients with cancer or renal failure, fat is the principal or the only constituent of weight gain, with little accrual of skeletal muscle or other components of fat-free mass. Among the many side effects of the use of MA, suppression of testosterone and estrogen production is prominent. Before the common use of other effective androgen suppressive treatments (flutamide, bicalutamide) in men with prostate cancer, MA was commonly used in this setting. Indeed, in older men, use of MA results in near-castrate levels of testosterone. MA has also been used to suppress estrogen levels in women with breast cancer.
The study published this month in JCEM examined the combined effects of testosterone and MA on the composition of weight gain in patients with HIV-associated wasting. This study demonstrates, once again, that MA has a substantial effect on appetite and body weight, with fat gain the principal component of the increase in body weight. However, fat-free mass was also increased along with total body weight in this trial, similar to a previous examination of the effect of MA on weight gain in patients with HIV-associated weight loss. Mulligan et al.showed that testosterone was suppressed, and testosterone replacement had no effect on the composition of the weight gain; furthermore, MA administration resulted in decreased libido. This suppressive effect of MA on testosterone production and in blocking the effects of testosterone on lean body mass accrual should be carefully considered before using MA in this patient population. Loss of lean mass in HIV patients is strongly linked to low androgen levels.
A number of unanswered questions concerning the effects of MA remain. Its use must be carefully considered and carefully managed. If an improvement in appetite and a gain in fat mass are desirable goals in the management of cachexia or involuntary weight loss, MA remains one of the most potent orexigenic agents currently available. Its use must be weighed against the potential for adrenal suppression and suppression of androgen production. Because of its antiandrogen properties, the antianabolic effects of MA are not ameliorated by testosterone administration.

 


 

10. What is the most important information I should know about Megestrol Acetatepols?aasraw

 

Megestrol acetate powder can harm an unborn baby or cause birth defects. Do not use megestrol if you are pregnant.
Before you take megestrol acetate powder, tell your doctor if you have diabetes or a history of stroke or blood clot.
Your dosage needs may change if you have surgery, are ill, are under stress, or have an infection. Do not change your medication dose or schedule without your doctor’s advice.
Megace ES contains a higher concentration of megestrol acetate powder than Megace. Ask your pharmacist if you have any questions about the medicine you receive at the pharmacy.

The most comprehensive introduction for Megestrol acetate powder | AASraw

 


 

11. Where can I get more information on Megestrol Acetate?aasraw

 

♣ CAS: 595-33-5
♣ Brand name: Megace®, Megace® ES
♣ www.aasraw.com

 


 

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